Dosage should be adjusted for each person. Some people do not tolerate L-glutamine very well, so introduce it slowly and carefuly. The common dose range is 6 to 25 grams divided into 3 doses per day, 30 minutes before meals.

Glutamine may increase T-cell attack in Crohn's disease. In the Crohn's patient glutamine may also be metabolized into citrulline, which is converted to arginine, a substrate for nitric oxide sythesis. Excessive nitric oxide has been shown to contribute to tissue injury and inflammation in Crohn's disease. L-glutamine seems to be effective only in ulcerative colitis.

A clinical study of ulcerative colitis patients showed that feeding 30 g daily of glutamine-rich foodstuff for four weeks resulted in significant clinical and endoscopic improvement, independent of disease state. Disease exacerbation returned when the treatment was discontinued.

It has also been suggested that cabbage juice consumption may provide benefit to patients with gastric ulcers and gastritis, by virtue of its high glutamine content.

So for those of us with Colitis it is definitely worth a try. If you can source any cabbage juice please let us know in our forum!!

Best of Luck,

Eat-right.ie